AAAR 31st Annual Conference
October 8-12, 2012
Hyatt Regency Minneapolis
Minneapolis, Minnesota, USA
Abstract View
Evaluation of Antimicrobial Durability on Natural Product Nanoparticle-Deposited Air Filter
GI BYOUNG HWANG, Bo Mi Kwon, Chu Won Nho, Jae Hee Jung, Gwi Nam Bae, Korea Institute of Science and Technology
Abstract Number: 309 Working Group: Health Related Aerosols
Abstract Bioaerosols contain airborne viruses, fungi, bacteria, and fragments of organisms. They can cause a variety of disease including infections, hypersensitivities, and toxic reactions and spread widely with air stream. Thus, it is important to control the concentration and viability of bioaerosols in order to protect human health. Recently, the air filtration treatment using natural products has been considered as the most practical way because some of natural products are lethal to microorganism as well as relatively less harmful to human comparing with other antimicrobial substances. In this study, we evaluated the antimicrobial durability on natural product nanoparticle-deposited air filter for four months.
Nanoparticles of Sophora flavescens were deposited on the surface of filter fiber through the thermal-nebulization process. Sophora flavescens is known to have various biological activities such as antibacterial or antifungal function and anticancer. The fabricated filters were stored at 20oC and relative humidity of 25%. Every month we confirmed the inactivation efficiency of the filter against E coli bacterial bioaerosol and the quantitative change on major chemical components (kurarinone, sophoraflavanone G, and kuraridin) of Sophora flavescens. In addition, the morphology change of the nanoparticles on filter was investigated using SEM.
The inactivation efficiency of the antimicrobial filter where natural product nanoparticles were deposited for 3min was approximately 90% and the efficiency kept for 3 months. And, during the same period, the major chemical components did not change. After three months, however, the inactivation efficiency decreased to 44%, and the amount of major chemical components reduced by 32.5%. The morphology of the nanoparticles did not change for four months.