AAAR 35th Annual Conference October 17 - October 21, 2016 Oregon Convention Center Portland, Oregon, USA
Abstract View
Hydrogen Peroxide Produced by Carbonaceous Particles in Physiologically Relevant Medium
Dan Hinz, Jeff Barnes, Clara Gutierrez, JUSTIN RODRIGUEZ, Juan Rodriguez, Anne Johansen, Central Washington University
Abstract Number: 460 Working Group: Health Related Aerosols
Abstract The detrimental effects of carbonaceous nanoparticles emitted from fuel combustion are well-known, and despite strong indications that one potential mechanism is driven by the in vivo production of reactive oxygen species (ROS), consequential particle characteristics remain elusive. Here, experiments were carried out to investigate the production of hydrogen peroxide (H$_2O$_2), an ROS, as a function of soot characteristics in the presence of biological electron donors at biologically representative low concentrations. Results indicate that the presence of soot is essential in the continuous production of H$_2O$_2 at concentrations on the order of hundreds of nM and that a small redox-active pool of iron is likely responsible for the conversion of H$_2O$_2 to the most potent ROS, namely hydroxyl radical (OH$^.). Data from this study increase our understanding of the reactivity of carbonaceous particles in a variety of settings.