10th International Aerosol Conference September 2 - September 7, 2018 America's Center Convention Complex St. Louis, Missouri, USA
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Aerosol Characterization of High-powered Electronic Nicotine Delivery Systems (ENDS)
SUVAJYOTI GUHA, Seyed Ahmad Reza Dibaji, Samanthi Wickramasekara, Berk Oktem, Matthew R. Myers, U.S. Food and Drug Administration, CDRH
Abstract Number: 1219 Working Group: Health Related Aerosols
Abstract The use of electronic cigarettes, referred to here as ENDS (electronic nicotine delivery systems), has continued to grow in the last ten years. There is limited published data on the physical and chemical characterization of the latest fourth generation ENDS. These devices can supply up to 300 Watts (W) of power, compared with the 1-10 W range of previous generations. Furthermore, the heating coils aerosolize the e-liquid by direct contact, and have been reported to reach high temperatures (around 300 – 400 degree Celcius). Such high temperatures can break down e-liquids (including the carrier liquids propylene glycol (PG) and vegetable glycerin (VG)), yielding substantial amounts of aldehydes and acrolein, which can produce serious health effects.
The objective of this study is two-fold. The first is to investigate the mechanism of the aerosol formation in the latest ENDS by using multiple orthogonal characterization techniques with different temporal resolutions. The second is to investigate the impact of the high coil temperatures, as well as the PG/VG concentrations on the aerosol particle size, and its chemical constituents (both organic and inorganic). Our preliminary results suggest that fourth generation ENDS produce aerosols containing particles with multimodal size distributions that range from a few nanometers to several micrometers. Temporal resolution also appears to strongly influence the modes that can be detected.
Acknowledgement – The funding for this research was provided by Center for Tobacco Products, U.S. Food and Drug Administration