Abstract Number: 671 Working Group: Health Related Aerosols
Abstract Ambient particulate matter (PM) pollution itself ranked 4$^(th) attributing burden of diseases for East Asia. Risk of urban PM pollution has been reported as moderate to high for cardiovascular, circulatory and pulmonary diseases for developed countries. However, such investigation is lacking for densely populated and rapidly growing countries like India were PM concentration level and composition are expected to be different and may be leading to more severe impact on health. Present study focuses on development of statistical relationship of ambient concentration of PM$_(2.5) with pulmonary and cardiovascular functions during January 2012 to April 2013. The subjects were recruited based on standard questionnaire survey designed by American thoracic society and modified for present study. A total number of 100 healthy subjects living in IIT Delhi from last 3 years or more were recruited for monitoring. Morning and evening pulmonary functions [i.e. force vital capacity (FVC); force expiratory volume in 1 second (FEV$_1); force expiratory flow rate (FEFR); (FEV$_1/FVC)] were measured repeatedly among all 100 subjects of average age 23 years (17-62 years). Simultaneously 8 hours ambulatory electrocardiography were conducted to monitor heart rate variability (HRV) functions [i.e. standard deviation of all NN intervals; square root of the mean squared successive NN interval differences; proportion of number of interval differences of successive NN intervals greater than 50 millisecond to total number of NN interval] repeatedly among 37 subjects of average age of 23 years (20-29 years). High PM$_(2.5) concentration was observed in January 2013 [168±88 mcg/m$^3 (day), 261±158 mcg/m$^3 (night)] while day time low was observed in April [71±32 mcg/m$^3] and night time low was observed in March [132±71 mcg/m$^3]. The multi-variant linear regression for FVC and SDNN perform moderately (R$^2=0.5) for lag$_3 day and lag$_3 night concentrations. This paper will discuss the relationship between PM$_(2.5) concentration with pulmonary and HRV functions.