10th International Aerosol Conference
September 2 - September 7, 2018
America's Center Convention Complex
St. Louis, Missouri, USA

Abstract View


The Effect of Humidity on the Viability of Aerosolised Bacterial Agents

EMMA KEYSER, Carwyn Davies, DSTL

     Abstract Number: 205
     Working Group: Infectious Bioaerosol

Abstract
In the event of an aerosol release of a biological agent, there is a need to understand the survival characteristics to evaluate the potential downwind impact. This is of vital importance for potential biological warfare agents, to assess the downwind hazard following release. To develop an understanding of the potential impact, it is necessary to investigate how different and varying environmental parameters can affect these aerosols. By altering these environmental parameters in a controlled laboratory environment, a full assessment of the survival characteristics of each pathogen can be determined.

Humidity is an important and variable factor that can have consequences on the stability and characteristics of a bioaerosol. Previous research, investigating the suspension of an aerosol over a prolonged period of time, has shown that relative humidity can affect the biological stability of a pathogen. Due to differing characteristics of individual pathogens, the impact of changing parameters, including humidity is likely to differ. For example, those pathogens that naturally thrive in wetter environments may benefit from higher levels of humidity, which may have a more detrimental impact on those that thrive naturally in relatively dry environments.

This study presents data showing the effects of different relative humidities on the stability and viability of a range of different pathogens contained within small particle aerosols over short distances and time from generation. Each pathogen was aerosolized at a range of humidities and evaluated using spray factor. Spray factor is one of the most effective ways of determining aerosol stability, and is calculated by taking the aerosol output and dividing it by the original concentration of the aerosol suspension. The spray factor was evaluated for a range of humidities for three different pathogens, including spore forming and vegetative cells.

Content includes material subject to © Crown copyright (2017), Dstl. This material is licensed under the terms of the Open Government Licence except where otherwise stated. To view this licence, visit http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3 or +write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gsi.gov.uk