Simultaneous Puff and Puff Associated Respiration Topography in the Natural Environment for Juul Ecig
RISA ROBINSON, Shehan Jayasekera, Edward Hensel, Rochester Institute of Technology
Abstract Number: 583
Working Group: Health-Related Aerosols
Abstract
Background: Modeling particle deposition in the lung of inhaled tobacco product users requires knowledge of the aerosol particle concentration, particle size and flow conditions of the aerosol. Methods for measuring concentration and particle size of aerosols are well established. However, methods for measuring puff topography and puff associated respiration (PAR) topography, particularly in the natural environment are lacking. Tobacco product users inhale in two part pattern- puffing followed by deep inhalation of the puff mixed with clean air. Without an accurate account of the complex flow pattern the aerosol experiences while traveling through the in the respiratory tract, accurate particle deposition modeling is not possible.
Method: Participants were asked to use a Juul monitor with Juul Virginia Tobacco eliquid having either 3% or 5% nicotine content, whichever matched their usual nicotine level. Participants were monitored for 24 hours in their natural environment. The wPUM Juul topography monitor was used to capture the time, flow rate and duration of every puff taken. Simultaneously, a sensorized wearable garment was used to measure chest motion which was associated with each participants inhalation volume.
Results: We recruited 72 regular ecig users from the Rochester, NY area. Of these, n=64 participants completed the study and n=55 completed the data quality check for puff topography and 39 passed the quality check for puff and PAR topography. Results are reported for the resulting n=39 participants.
Mean (STD) puff associated inhalation volume was 104 (785). Mean (STD) puff topography parameters were 30 (7) mL/s flow rate, 3.5 (1) sec duration, and 104 (6) puff volume.
Conclusions: This study demonstrated successful simultaneous capture of puff and puff associated respiration in the natural environment. Data should be used as in put to lung deposition models to accurately determine the deposition efficiency.