AAAR 35th Annual Conference October 17 - October 21, 2016 Oregon Convention Center Portland, Oregon, USA
Abstract View
Establishment and Characterization of a Mouse Chamber for Investigating Health Effects
XINZE PENG, David R. Cocker III, David Lo, Emma Aronson, University of California, Riverside
Abstract Number: 583 Working Group: Aerosol Exposure
Abstract Recently we completed a new 540 L chamber for studying the exposure of mice to multiple air contaminants. The chamber can simultaneously control for multiple VOCs, particulate size and mass concentrations (synthetic or directly from source), active soils and/or pollens. The design is a result of a collaboration between the UC Riverside School of Medicine, CE-CERT, and plant/botany sciences. The system provides for controlled and well characterized whole animal exposures (typical duration of 1-2 weeks) where dosage is by inhalation of the air pollutants. Uniform dispersion and exposure stability of each class of air pollutants was characterized. Stability, range, and characterization of the system are summarized along with generation of air pollutants by the test subjects.